Buprenorphine-Sustained Release Alters Hemodynamic Parameters in a Rat Burn Model
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چکیده
منابع مشابه
Antinociceptive effects of sustained-release buprenorphine in a model of incisional pain in rats (Rattus norvegicus).
Effective management of postoperative pain is an essential component of the care and welfare of laboratory animals. A sustained-release formulation of buprenorphine (Bup-SR) has recently been introduced to the veterinary market and has been reported to provide analgesia for as long as 72 h. Using evoked mechanical and thermal hypersensitivity tests, we here evaluated the antinociceptive effects...
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Introduction: Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women during reproductive ages. This syndrome is associated with disruption of sex hormone levels. Studies have shown that endurance of the heart to ischemia-reperfusion (I/R) injury can be affected by sex hormones. In the present study, the rate of cardiac tolerance against I/R injury in the PCOS ra...
متن کاملPostoperative Analgesia Due to Sustained-Release Buprenorphine, Sustained-Release Meloxicam, and Carprofen Gel in a Model of Incisional Pain in Rats (Rattus norvegicus).
Postoperative analgesia in laboratory rats is complicated by the frequent handling associated with common analgesic dosing requirements. Here, we evaluated sustained-release buprenorphine (Bup-SR), sustained-release meloxicam (Melox-SR), and carprofen gel (CG) as refinements for postoperative analgesia. The aim of this study was to investigate whether postoperative administration of Bup-SR, Mel...
متن کاملProlonged hemodynamic effectiveness of sustained release isosorbide dinitrate.
Communications for this section will be puhlL,hed as space and priorities permit. The comments should not exceed 350 words in length, with a maximum of five references; one figure or table can be printed. Exceptions may occur under particular circumstances. Cantributioma may include cornments on articles published in thLs periodical, or they may be reports of unique educational character. Speci...
متن کاملPharmacokinetics of a single subcutaneous dose of sustained release buprenorphine in northern elephant seals (Mirounga angustirostris).
Information regarding analgesics in pinnipeds is limited. This study aimed to establish the pharmacokinetic parameters of a single subcutaneous dose of sustained release buprenorphine (Buprenorphine SR) in juvenile northern elephant seals (Mirounga angustirostris) with regard to its potential to provide long-lasting analgesia that requires infrequent dosing. Seals (n=26) were administered a sin...
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ژورنال
عنوان ژورنال: Journal of Surgical Research
سال: 2018
ISSN: 0022-4804
DOI: 10.1016/j.jss.2018.03.016